Hormone Replacement Therapy (We are no longer accepting cases on this product)
Before the 1960s and 1970s, estrogen alone was the dominant hormone prescribed for menopausal women. However, the increased risk of endometrial cancer led to the addition of progestins combined with estrogen for women who had not had a hysterectomy. Since the mid-1980s, estrogen/progestin therapy has been commonly prescribed for relief of menopausal symptoms.
In 2001, approximately 22.3 million prescriptions were written for Prempro (a brand-name estrogen/progestin combination). This hormone replacement therapy (“HRT”) has been prescribed for relief of menopausal symptoms and prevention of osteoporosis. Doctors have thought that long-term use was useful in helping prevent a range of chronic conditions, including heart disease.
The Women’s Health Initiative, a national fifteen-year study, has concluded that women taking Hormone Replacements are at increased risk of breast cancer, coronary heart disease, stroke and pulmonary embolism.