Type 2 diabetes affects millions of Americans. These patients rely on safe and effective drugs to control their disease. Two medications marketed by pharmaceutical giant AstraZeneca have sparked safety concerns over the years — Onglyza® and Kombiglyze XR®.
A clinical trial indicated that patients who took these drugs faced a 27 percent increase in heart failure risk. Further, there was a rise in the rate of mortality (death) due to all causes among the group of people taking these medications.
In response to the growing Type 2 diabetes epidemic, new drugs are constantly being released. Onglyza® was first released in the U.S. in 2009. It contains an incretin mimetic and works by boosting incretins that release insulin after meals.
In 2010, another new medication for Type 2 diabetes hit the market — Kombiglyze XR®. This extended-release drug offered strong glycemic control. Both drugs were approved by the Food and Drug Administration (FDA) but have since been questioned for safety.
Both Onglyza® and Kombiglyze XR® contain saxagliptin. Saxagliptin has been under investigation by the FDA as part of an ongoing investigation regarding the cardiovascular risks of Type 2 diabetes drugs.
In 2016, the FDA announced that Type 2 diabetes drugs containing saxagliptin may put patients at an increased risk for heart failure. Patients who have a history of heart disease are at the greatest risk. New warnings have since been added to the labels of Onglyza® and Kombiglyze XR®.
Patients with heart failure may require surgery, ventricular assist devices, new medications, and diet or lifestyle changes.
Symptoms often include:
Some studies have indicated an increased risk of pancreatic cancer for patients taking drugs like Onglyza® and Kombiglyze XR®. Researchers found that patients taking these drugs had inflammation of the pancreas or precancerous cells in the pancreatic tissue. The FDA continues to investigate this matter.
If you suffered heart failure or developed cancer after taking one of these medications, the attorneys at Ward Black Law want to hear from you. We have decades of experience representing innocent people who have been harmed by dangerous drugs. We can guide you through the steps involved with filing a lawsuit and serve as your powerful voice to pursue compensation to which you may be entitled. There are no fees unless we win your case together.